Silicon Neuroma: God Rolls for PvE & PvP and How to get it

by | Sep 28, 2022

The Silicon Neuroma is a Kinetic Aggressive Sniper Rifle archetype, firing at 72 rounds per minute. This weapon was originally released with the Curse of Osiris DLC back in Year 1, and now it returns to us as a farmable Nightfall weapon.

In this guide, we tell you where to find the weapon, how to farm it, and what are the best rolls for PvE and PvP.

ArtNameArchetypeRarityAmmo?Element?RequirementsIn loot pool?AmmoElementTierExcelsSourceCraftable?RequiresReleasedSlotCan be Crafted?Best of?Top Perk?
Silicon Neuroma artSilicon NeuromaAggressiveLegendarySpecialKineticFree-to-PlayYesSpecial ammo Destiny 2 SpecialKinetic symbol Destiny 2 Kinetic
A › Strong
PvE + PvPNightfall: The OrdealsError icon V2 NoDestiny 2 Icon (final) Destiny 2
Free-to-Play
Season 16KineticNoTop-tier

How to get the Silicon Neuroma in 2022

The Silicon Neuroma first came out with Curse of Osiris (a much panned DLC) back in Year 1 of Destiny 2. Three years later, it returns to us with some solid perks, especially for PvP, as a Nightfall-exclusive reward.

Nightfall Weapon rotation for 2022

There are 14 Nightfall-specific weapons in total, and as of Season of Plunder (S18), only 6 out of the 14 total weapons are currently on rotation, with only one dropping each week. This means you can only farm the Silicon Neuroma sniper once every six weeks!

2022 Nightfall weapon rotation

ArtWeaponTypeElementAmmoRotationWeek #
Scintillation art Destiny 2ScintillationLinear Fusion RifleStrand Element StrandHeavy ammo Destiny 2 HeavyFebruary 4, 2025Week 1
Rake Angle art Destiny 2Rake AngleGlaiveStasis StasisSpecial ammo Destiny 2 SpecialFebruary 11, 2025Week 2
Shadow Price art Destiny 2Shadow PriceAuto RifleArc ArcPrimary ammo Destiny 2 PrimaryFebruary 18, 2025Week 3
The Palindrome artThe PalindromeHand CannonArc ArcPrimary ammo Destiny 2 PrimaryFebruary 25, 2025Week 4
PLUG ONE.1 artPLUG ONE.1Fusion RifleArc ArcSpecial ammo Destiny 2 SpecialMarch 4, 2025Week 5
Lotus-Eater art Destiny 2Lotus-EaterSidearmVoid VoidSpecial ammo Destiny 2 SpecialMarch 11, 2025Week 6
Scintillation art Destiny 2ScintillationLinear Fusion RifleStrand Element StrandHeavy ammo Destiny 2 HeavyMarch 18, 2025Week 7
Rake Angle art Destiny 2Rake AngleGlaiveStasis StasisSpecial ammo Destiny 2 SpecialMarch 25, 2025Week 8
Shadow Price art Destiny 2Shadow PriceAuto RifleArc ArcPrimary ammo Destiny 2 PrimaryApril 1, 2025Week 9
The Palindrome artThe PalindromeHand CannonArc ArcPrimary ammo Destiny 2 PrimaryApril 8, 2025Week 10
PLUG ONE.1 artPLUG ONE.1Fusion RifleArc ArcSpecial ammo Destiny 2 SpecialApril 15, 2025Week 11
Lotus-Eater art Destiny 2Lotus-EaterSidearmVoid VoidSpecial ammo Destiny 2 SpecialApril 22, 2025Week 12
Scintillation art Destiny 2ScintillationLinear Fusion RifleStrand Element StrandHeavy ammo Destiny 2 HeavyApril 29, 2025Week 13
Rake Angle art Destiny 2Rake AngleGlaiveStasis StasisSpecial ammo Destiny 2 SpecialMay 6, 2025Week 14
Shadow Price art Destiny 2Shadow PriceAuto RifleArc ArcPrimary ammo Destiny 2 PrimaryMay 13, 2025Week 15
The Palindrome artThe PalindromeHand CannonArc ArcPrimary ammo Destiny 2 PrimaryMay 20, 2025Week 16
PLUG ONE.1 artPLUG ONE.1Fusion RifleArc ArcSpecial ammo Destiny 2 SpecialMay 27, 2025Week 17
Lotus-Eater art Destiny 2Lotus-EaterSidearmVoid VoidSpecial ammo Destiny 2 SpecialJune 3, 2025Week 18

This guide will always highlight the Nightfall weapons this week, as well as the schedule for the coming weeks.

Nightfall weapons

How good is the Silicon Neuroma today

Being an aggressive frame sniper, Silicon Neuroma has the benefit of a whopping 158 bodyshot damage in PvP, and with Succession being the only other popular Aggressive sniper in the Kinetic slot, it doesn’t have a lot of competition. However, players may prefer Adaptive frame snipers such as Eye of Sol from Trials of Osiris or the Defiance of Yasmin from King’s Fall.

In PvE, however, Silicon Neuroma lacks most of the strong perks that make snipers usable in endgame content, and with Arbalest being such a powerhouse right now, it’s hard to recommend Silicon over many other Kinetic options.

For all these reasons, we put Silicon Neuroma in the B tier. Its undeniable strength in PvP makes up for its lackluster presence in PvE.

  • B Tier – Average: A decent choice that can be lethal in the hands of a skilled player.

Best alternatives:

ArtNameArchetypeRarityAmmo?Element?RequirementsIn loot pool?AmmoElementTierExcelsSourceCraftable?RequiresReleasedSlotCan be Crafted?Best of?Top Perk?
Defiance of Yasmin artDefiance of YasminAdaptiveLegendarySpecialKineticFree-to-PlayYesSpecial ammo Destiny 2 SpecialKinetic symbol Destiny 2 Kinetic
A › Strong
PvE + PvPKing's Fall RaidCheckmark icon V3 YesDestiny 2 Icon (final) Destiny 2
Free-to-Play
Season 18KineticCraftableTop-tier
Eye of Sol artEye of SolAdaptiveLegendarySpecialKineticThe Final ShapeNoSpecial ammo Destiny 2 SpecialKinetic symbol Destiny 2 Kinetic
S › Best
PvPTrials of OsirisError icon V2 NoThe Final Shape Icon (final) Destiny 2
The Final Shape
Season 10KineticNoTop-tier
Succession Destiny 2 artSuccessionAggressiveLegendarySpecialKineticBeyond Light PackYesSpecial ammo Destiny 2 SpecialKinetic symbol Destiny 2 Kinetic
S › Best
PvE + PvPDeep Stone Crypt RaidCheckmark icon V3 YesBeyond Light Icon (final) Destiny 2
Beyond Light Pack
Season 12KineticCraftableTop-tierReconstruction

Best Silicon Neuroma Rolls for PvE and PvP

Once you’ve identified the right week to farm, you’ll want to run as many Nightfalls (and at the higher difficulty possible) as possible to increase your chances of finding a god roll. Among the several strong possible rolls out there, these are our favorites, the combinations we consider god rolls.

Silicon Neuroma roll

A Silicon Neuroma roll, Destiny 2

Silicon Neuroma PvP god roll

For PvP, you want high Handling and High Stability, therefore Fluted Barrel is by far the best choice. For your magazine, you’ll want Ricochet Rounds or Flared Magwell for that bump to stability, and for your perks, you want Snapshot Sights and Opening Shot.

  • Barrel: Fluted Barrel or Polygonal Rifling
  • Magazine: Ricochet Rounds or Flared Magwell
  • Perk 1: Snapshot Sights
  • Perk 2: Opening Shot

Silicon Neuroma PvE god roll

For your PvE perks, your barrels don’t matter too much. However, you may still want to opt for Fluted Barrel for that increase in handling and stability. For your magazine, Appended Mag is the way to go as Silicon has a very low magazine size of 3, therefore increasing it as much as possible is a priority. For your perks, you want Triple Tap and either Firing Line or Frenzy. These perks will allow you to deal as much damage as possible and turn this sniper into a decent backup option for DPS.

  • Barrel: Fluted Barrel
  • Magazine: Appended Mag
  • Perk 1: Triple Tap
  • Perk 2: Firing Line or Frenzy

Silicon Neuroma Adept

If you’re courageous enough to tackle Nightfalls on Grandmaster difficulty, you could earn an Adept version of the Silicon Neuroma. On top of serving as bragging rights, Adept variants of weapons have more perks per column, give even more stats when Masterworked, and can accept unique Adept mods.

Be aware that Grandmaster Nightfalls are only available during the second half of the season.

About The Author

Ric Molina
Ric Molina
I've been covering gaming since 2012, and some of my work has been featured by large brands, including MSN.com, Forbes, Rock Paper Shotgun, and more. I've been obsessed with Destiny 2 (and now Diablo 4) for years now, and I hope to provide new and returning players with the guides and resources I wish I had when I first started.
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