Silicon Neuroma: God Rolls for PvE & PvP and How to get it

by | Sep 28, 2022

The Silicon Neuroma is a Kinetic Aggressive Sniper Rifle archetype, firing at 72 rounds per minute. This weapon was originally released with the Curse of Osiris DLC back in Year 1, and now it returns to us as a farmable Nightfall weapon.

In this guide, we tell you where to find the weapon, how to farm it, and what are the best rolls for PvE and PvP.

ArtWeaponArchetypeRarityAmmoElementRequirementsIn loot pool?Ammo?Element?TierExcelsSourceCraftable?RequiresReleasedSlotCan be Crafted?Best of?Top Perk?
Silicon Neuroma artSilicon NeuromaAggressiveLegendarySpecialKineticFree-to-PlayYesSpecial ammo Destiny 2 SpecialKinetic symbol Destiny 2 Kinetic


PvE + PvPNightfall: The OrdealsError icon V2Free to Play Destiny 2 icon
Season 16KineticNoTop-tier

How to get the Silicon Neuroma in 2022

The Silicon Neuroma first came out with Curse of Osiris (a much panned DLC) back in Year 1 of Destiny 2. Three years later, it returns to us with some solid perks, especially for PvP, as a Nightfall-exclusive reward.

Nightfall Weapon rotation for 2022

There are 14 Nightfall-specific weapons in total, and as of Season of Plunder (S18), only 6 out of the 14 total weapons are currently on rotation, with only one dropping each week. This means you can only farm the Silicon Neuroma sniper once every six weeks!

2022 Nightfall weapon rotation

ArtWeaponTypeElementAmmoRotationWeek #
Warden's Law artWarden's LawHand CannonKinetic symbol Destiny 2 KineticPrimary ammo Destiny 2 Primary28 November 2023Week 1
Loaded Question art Destiny 2Loaded QuestionFusion RifleArc ArcSpecial ammo Destiny 2 Special5 December 2023Week 2
12 December 2023Week 3
19 December 2023Week 4
26 December 2023Week 5
2 January 2024Week 6
9 January 2024Week 7
16 January 2024Week 8
23 January 2024Week 9
30 January 2024Week 10
6 February 2024Week 11
13 February 2024Week 12
20 February 2024Week 13
27 February 2024Week 14
5 March 2024Week 15
12 March 2024Week 16
19 March 2024Week 17
26 March 2024Week 18
2 April 2024Week 19
9 April 2024Week 20
16 April 2024Week 21
23 April 2024Week 22
30 April 2024Week 23
7 May 2024Week 24
14 May 2024Week 25
21 May 2024Week 26
28 May 2024Week 27

This guide will always highlight the Nightfall weapons this week, as well as the schedule for the coming weeks.

Nightfall weapons

How good is the Silicon Neuroma today

Being an aggressive frame sniper, Silicon Neuroma has the benefit of a whopping 158 bodyshot damage in PvP, and with Succession being the only other popular Aggressive sniper in the Kinetic slot, it doesn’t have a lot of competition. However, players may prefer Adaptive frame snipers such as Eye of Sol from Trials of Osiris or the Defiance of Yasmin from King’s Fall.

In PvE, however, Silicon Neuroma lacks most of the strong perks that make snipers usable in endgame content, and with Arbalest being such a powerhouse right now, it’s hard to recommend Silicon over many other Kinetic options.

For all these reasons, we put Silicon Neuroma in the B tier. Its undeniable strength in PvP makes up for its lackluster presence in PvE.

  • B Tier – Average: A decent choice that can be lethal in the hands of a skilled player.

Best alternatives:

ArtWeaponArchetypeRarityAmmoElementRequirementsIn loot pool?Ammo?Element?TierExcelsSourceCraftable?RequiresReleasedSlotCan be Crafted?Best of?Top Perk?
Defiance of Yasmin artDefiance of YasminAdaptiveLegendarySpecialKineticFree-to-PlayYesSpecial ammo Destiny 2 SpecialKinetic symbol Destiny 2 Kinetic


PvE + PvPKing's Fall RaidCheckmark icon V3Free to Play Destiny 2 icon
Season 18KineticCraftableTop-tier
Eye of Sol artEye of SolAdaptiveLegendarySpecialKineticLightfallNoSpecial ammo Destiny 2 SpecialKinetic symbol Destiny 2 Kinetic


PvPTrials of OsirisError icon V2Lightfall Preorder icon
Season 10KineticNoTop-tier
Succession Destiny 2 artSuccessionAggressiveLegendarySpecialKineticBeyond LightYesSpecial ammo Destiny 2 SpecialKinetic symbol Destiny 2 Kinetic


PvE + PvPDeep Stone Crypt RaidCheckmark icon V3Beyond Light Destiny 2 icon
Beyond Light
Season 12KineticCraftableTop-tierReconstruction

Best Silicon Neuroma Rolls for PvE and PvP

Once you’ve identified the right week to farm, you’ll want to run as many Nightfalls (and at the higher difficulty possible) as possible to increase your chances of finding a god roll. Among the several strong possible rolls out there, these are our favorites, the combinations we consider god rolls.

Silicon Neuroma roll

A Silicon Neuroma roll, Destiny 2

Silicon Neuroma PvP god roll

For PvP, you want high Handling and High Stability, therefore Fluted Barrel is by far the best choice. For your magazine, you’ll want Ricochet Rounds or Flared Magwell for that bump to stability, and for your perks, you want Snapshot Sights and Opening Shot.

  • Barrel: Fluted Barrel or Polygonal Rifling
  • Magazine: Ricochet Rounds or Flared Magwell
  • Perk 1: Snapshot Sights
  • Perk 2: Opening Shot

Silicon Neuroma PvE god roll

For your PvE perks, your barrels don’t matter too much. However, you may still want to opt for Fluted Barrel for that increase in handling and stability. For your magazine, Appended Mag is the way to go as Silicon has a very low magazine size of 3, therefore increasing it as much as possible is a priority. For your perks, you want Triple Tap and either Firing Line or Frenzy. These perks will allow you to deal as much damage as possible and turn this sniper into a decent backup option for DPS.

  • Barrel: Fluted Barrel
  • Magazine: Appended Mag
  • Perk 1: Triple Tap
  • Perk 2: Firing Line or Frenzy

Silicon Neuroma Adept

If you’re courageous enough to tackle Nightfalls on Grandmaster difficulty, you could earn an Adept version of the Silicon Neuroma. On top of serving as bragging rights, Adept variants of weapons have more perks per column, give even more stats when Masterworked, and can accept unique Adept mods.

Be aware that Grandmaster Nightfalls are only available during the second half of the season.

About The Author

Ric Molina
Ric Molina
I've been covering gaming since 2012, and some of my work has been featured by large brands, including, Forbes, Rock Paper Shotgun, and more. I've been obsessed with Destiny 2 (and now Diablo 4) for years now, and I hope to provide new and returning players with the guides and resources I wish I had when I first started.
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